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In a week when pregnant women have finally been given the OK to have their jabs, omicron is moving super-fast. It’s doubling in no time and has already put delta into the shade. Those in power are dithering again, uncertain whether to wait and let everyone have a good Christmas first, or apply lockdown-style restrictions now and save lives. Whatever you think about the government, theirs isn’t a job we’d want right now!
Here’s the latest news about omicron, direct from the scientists doing the research, via New Scientist magazine. Read this and you’ll be in a position of knowledge, hopefully able to make better decisions at a time when decision making is extremely difficult.
Dangerous omicron mutations and how they happened
Omicron has 50-ish mutations compared to the original covid that came out of China, 30 of which are in its outer spike protein, the place our bodies’ antibodies target. These changes reduce the protective power of the antibodies we get from vaccinations and previous covid infections, and this ‘particularly dangerous’ set of mutations is apparently very worrying.
Nobody knows how omicron managed to acquire so many dangerous mutations, and we probably never will. It could have happened thanks to just one immunocompromised person. Some speculate it may have been someone with HIV in South Africa who wasn’t getting the treatment they needed. Viruses are usually killed by a normal immune response but if your system is compromised some viruses can keep replicating, ultimately evolving into a virus that’s better at evading antibodies.
There’s another theory, that covid infected animals, collected mutations as it spread, then hopped back into humans. Some people have pinned the blame on mice in labs but there’s no evidence for that. It ‘seems highly unlikely’. Others wonder whether the new variant evolved slowly as it spread between humans, but there’s no evidence for that either. There’s also no evidence for the drug molnupiravir playing a part.
Where did omicron begin?
The earliest confirmed omicron cases were found in South Africa and Botswana, but the variant seems to have been spreading since early October. We still have no idea where it began, although it seems likely it arose in the south of Africa simply because that’s where we saw the first wave of omicron. None of the early cases found in other countries pre-date the first African cases.
How likely are we to be re-infected by omicron?
A new study of UK health workers reveals those who had the alpha variant before being double jabbed against the original virus have a worse antibody response to the original virus and beta, than those who had the original virus then been double jabbed. On the other hand the first group had better antibody responses to delta. As the head of the team said, “It’s very variant-specific and quite unpredictable. If you have got people in different parts of the globe exposed to different waves of infection, you have got people with different immune repertoires. It’s dangerous to draw too many conclusions.”
‘England must act before Christmas’ – but the public is already doing the decent thing
It’s interesting to see that, no matter what the official message is, ordinary people are wearing face masks again, steering clear of crowds, and cutting their festive plans down to a safer and more sensible size. While the politicians tear each other apart we seem to be quietly, sensibly getting on with keeping ourselves and the people we love safe.
If you’d like to explore the proven power of UVC LED light for killing covid stone dead in minutes, get in touch. In the meantime, happy festivities!