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If you’ve been watching hit HBO series
The Last of Us you’ll probably know more about fungi than you did before the story hit the TV screen. But it’s more than a mere horror show. There are more than 200,000 species of fungi out there, including moulds and yeasts, and a fungal pandemic isn’t out of the question. Take India, where alarm bells rang over the terrible black mould infections from the mould mucormycosis, which killed thousands of covid patients.
Fungal infections have been steadily creeping up for years. This is borne out by increasing numbers of warnings from laboratories, hospitals and health experts around the globe, revealing a sharp rise in potentially deadly fungal illnesses. These infections are raising the alarm at the highest levels in public health. And so far there are very few treatments.
Fungi are often completely harmless but it depends on your state of health. If you’re living with cancer, HIV, or diabetes you’re at serious risk. The same goes if you need major surgery involving a stay in intensive care, or you’ve already caught another kind of serious infection, simply because your immunity to every kind of disease is weakened.
The USA is showing some progress. Back in 2019, pre-covid, the USA’s Centers for Disease Control gave ‘urgent threat’ status to the deadly yeast Candida auris, which had turned up out of the blue ten years earlier and proved resistant to many - and often all - antifungal treatments. There’s also a resistant strain of Aspergillus fumigates on the loose in the USA thanks to farmers over-using antifungal treatments.
Along with new fungal threats, we’re seeing a parallel boom in the number of people vulnerable to them. Sophisticated treatments like chemotherapy, organ transplants, major surgery, and simply the number of years we’re surviving with diseases like diabetes, are all giving these new threats a foothold. And it means the worldwide fungal disease caseload is rocketing.
In response the WHO has released a global survey of fungal diseases, revealing which are the biggest threats to people’s health. Four pathogens were named as priorities. Antifungal-resistant Candida auris is a big issue in hospitals. Aspergillus fumigatus can kill, especially the drug-resistant strains. Candida albicans is another big issue in hospitals, and there’s Cryptococcus neoformans, which infects the brains of the immuno-vulnerable and primarily kills people with HIV. The WHO says all four should be watched, surveyed, researched, analysed, and effective ‘improvements in public health interventions’ made.
As we already know thanks to covid, which is surging again in the UK right now, we need to understand fungal threats before they arrive. It makes sense. If you don’t know what’s coming, how can you prepare?
So far, humanity hasn’t developed any anti-fungal vaccines. If we get a fungal epidemic, there’s no way we could develop, make and distribute vaccines in time to save lives. But in a world where many strains of fungi are resistant to every drug available, it’s urgent.
We can take a fair lesson from the fungal frog pandemic Chytrid disease, which in recent years has caused the greatest recorded loss of biodiversity... ever. So it’s good to see researchers at the USA’s Case Western Reserve University working hard to combat the deadly fungus Candida auris, developing a new treatment.
It’s also good to know how our UVC units take care of a list of potentially dangerous fungi, moulds, and yeasts, killing them quickly and safely. If you’d like to know more about protecting people in healthcare and other settings against fungal threats, we’d be pleased to discuss the potential with you.
Source:
https://www.gizmodo.com.au/2023/02/the-threat-of-killer-fungi-infections-is-growing-international-research-team-found/
https://www.msn.com/en-us/health/other/superbug-killers-cwru-researchers-develop-treatment-for-dangerous-drug-resistant-fungus/ar-AA17HRtB