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Dengue fever, tick-borne encephalitis and a deadly outbreak of botulism are bedevilling France at the moment. In Australia rampant listeria is causing havoc. 25 pupils and staff have been off sick with salmonella after an outbreak in a Scottish school. In Canada E.Coli is poisoning children in Calgary. In Turkey 88 people have been affected by botulism outbreak. Around the world, mycotoxin contamination of cereals and cereal-based products is a serious food safety issue. And in New York a lawsuit is cranking up for expensive action following a nasty food poisoning outbreak at a sushi and steakhouse.
It can be a challenge seeing when food and drink it contaminated. Now some clever people have come up with viral nanobots that can make nasty bacteria in food and drink glow. It’s great to hear when it can be so time consuming and tricky to test food and drink for harmful bacteria.
Viral nanobots make bacterial health threats glow
Drinking water and food are both tricky to test. In the UK, for example, our drinking water must be free from Ecoli, which causes food poisoning. But it’s hard to test for and even harder to pinpoint low microbial concentrations of it. So a team from New York’s Cornell University tried using bacteriophages as living nanobots to stick onto bacteria to make them easier to see.
The team used the gene editing tool CRISPR to change the bacteriophage’s DNA in two ways. The first change makes the infected E. coli glow in a similar way to deep sea shrimp. When they added the bacteriophages to water or liquid food, the infected E. coli bacteria lit up like a Christmas tree. The second tweak changes the structure of the viral duplicates inside the E. Coli so they stick to either cellulose or miniature magnetic particles, making them easier to collect.
A fast and easy way to see threats so they can be killed
It looks like the gene-edited bacteriophages can detect just 5 bacteria in 100 millilitres of fluid, and it took half the time to do the job compared to the usual methods. Using bacteriophages like this is really fast, and it helps that there are so many bacteriophages already out there in nature that find and attack bacteria. They usually target a single type of bacteria but they can be genetically engineered to make hybrids.
The team has already done exactly that in an effort to ‘see’ Listeria and Salmonella in food and water more easily. Apparently it won’t be long before designing and engineering brand-new bacteriophages from the bottom-up becomes reality. Once they’re spotted, killing food borne health threats is a relatively simple matter using proven UVC light tech like our units, which reliably destroy pathogens in every stage of the food processing and packaging journey.